What is Eysuvis?

EysuvisTM (loteprednol etabonate ophthalmic suspension) 0.25 percent is an ocular corticosteroid that is approved to treat the signs and symptoms of chronic dry eye. It is a short-term treatment that may be used for up to 2 weeks.1,2

Dry eye disease is a chronic condition that affects the tears and surface of the eye. Symptoms include:1,2

  • Tear film instability
  • Swelling
  • Discomfort
  • Visual disturbance
  • Damage to the surface of the eye

Roughly 80 percent of people with chronic dry eye have flares caused by various triggers. These flares may be challenging to manage.1,2

What are the ingredients?

The active ingredient in Eysuvis is a steroid called loteprednol etabonate.1

How does it work?

Eysuvis uses Ampplify® mucus-penetrating particle (MPP) Drug Delivery Technology. This technology helps the drug better penetrate target tissue on the surface of the eye. Eysuvis contains a steroid that targets the immune responses that cause flares.1

What are the possible side effects?

The most common side effect of Eysuvis is eye pain.2

Eysuvis may also cause increased pressure in the eye. This can cause optic nerve damage, visual problems, cataracts, delayed wound healing, and infection.2

These are not all the possible side effects of Eysuvis. Talk to your doctor about what to expect or if you experience any changes that concern you during treatment with Eysuvis.

Things to know about Eysuvis

Do not use Eysuvis (or any steroid eye drops) if you have an infection in the eye. Use caution if you have a history of herpes simplex or other viral infections of the eye.2

Steroid eye drops may delay healing and cause thinning of the cornea and sclera, causing perforation. Long-term use of steroid eye drops may also lead to fungal infections of the cornea.2

Before prescribing Eysuvis and with each refill, your doctor should examine your eyes.2

Using steroids for a long time can cause cataracts, glaucoma, and vision problems. If you have glaucoma, talk to your doctor before using Eysuvis.2

Steroids may weaken the immune system. This may increase the chance of eye infections or worsen a current infection.2

Wash hands well before use. Shake the bottle for 2 or 3 seconds before using. Do not allow the tip of the dropper to touch any surface.2

Remove contact lenses before using Eysuvis. Reinsert contact lenses 15 minutes after using Eysuvis.2

Before beginning treatment for chronic dry eye, tell your doctor about all your health conditions and any other drugs, vitamins, or supplements you are taking. This includes over-the-counter drugs.

For more information, read the full prescribing information of Eysuvis.

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Written by: Karen Berger | Last reviewed: April 2021